Página del residente-Fractura atípica de fémur asociada al uso de bifosfonatos

La alteración en la microarquitectura del hueso generada con la osteoporosis predispone a fracturas por fragilidad que impactan la calidad y el pronóstico de vida de millones de adultos mayores. Uno de los tratamientos actuales de la osteoporosis son los antiresortivos como los bifosfonatos. Con el auge del uso de bifosfonatos actualmente existe un incremento en la incidencia de los efectos adversos. Aunque su fisiopatología aún es debatida, existe una asociación entre el uso crónico de estos medicamentos y fracturas atípicas del fémur. Se reporta el caso de una paciente con uso crónico de alendronato por 10 años, quien presenta una fractura atípica subtrocantérica de fémur, con estudios de imágenes previos por presentar síntomas prodrómicos.

 

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fracturas atípicas de fémur
bifosfonatos
osteoporosis
alendronate